Open fractures: the BOAST standard, timings and the Gustilo–Anderson classification
The BOAST open fracture standard for FRCS (Tr & Orth): antibiotics within an hour, debridement at 12 or 24 hours, cover within 72 hours, and Gustilo–Anderson grading.
UK practice for open fractures is set by two documents that say the same thing: the British Orthopaedic Association Standard for Trauma on open fractures, written jointly with the British Association of Plastic, Reconstructive and Aesthetic Surgeons and last revised in December 2017, and the NICE guideline on complex fractures, NG37. Both are built on one idea — that an open fracture is a combined bone and soft-tissue injury, and that outcomes are best when orthopaedic and plastic surgeons plan and operate together. The written paper is set to this practice, so the timings below are worth knowing exactly.
1 hour
Intravenous antibiotics, from injury
12 hours
Debridement, solitary high-energy
24 hours
Debridement, low-energy
72 hours
Definitive soft-tissue cover
In the emergency department
The patient is assessed and resuscitated as a trauma patient first; the open fracture is rarely the injury that threatens life. Once that is done, the standard asks for a short and specific sequence.
Antibiotics. Intravenous prophylactic antibiotics as soon as possible, ideally within one hour of injury. The agent follows local policy; in practice the first dose is often given before the patient reaches hospital.
Neurovascular examination. The vascular and neurological status of the limb is examined and documented, and the examination is repeated systematically, particularly after reduction or the application of a splint.
Realign and splint. The limb is brought back into alignment and splinted.
The wound. It is handled only to remove gross contamination and to allow photography, then dressed with saline-soaked gauze under an occlusive film. Irrigation or ‘mini-washouts’ outside the operating theatre are not indicated, and the wound is not repeatedly uncovered.
Imaging and the plan. Trauma imaging follows the trauma network’s protocol. A management plan is agreed between the orthopaedic and plastic surgeons and written in the notes.
Where the patient goes matters as much as what is done on arrival. Patients with open fractures of long bones, the hindfoot or the midfoot are taken directly, or transferred, to a specialist centre that can provide orthoplastic care. Open fractures of the hand, wrist, forefoot and digits can be managed locally.
When to debride
The old rule that every open fracture must be debrided within six hours has gone. Published series did not show that operating inside six hours reduced infection, whereas operating at night with an inexperienced team and no plastic surgeon clearly had costs. The standard replaces a single deadline with three, according to contamination and energy.
Timing of surgical debridement, per the BOAST open fractures standard (2017). Debridement is performed by consultant orthopaedic and plastic surgeons working together.
Situation
Timing of debridement
Highly contaminated wound — agricultural, aquatic or sewage contamination
Immediately
Associated vascular compromise — compartment syndrome, or an arterial injury producing ischaemia
Immediately
Solitary high-energy open fracture
Within 12 hours of injury
All other low-energy open fractures
Within 24 hours of injury
Debridement means excision, not washing. The wound is extended along fasciotomy lines where possible, so that the incisions do not compromise later flap options; the bone ends are delivered; and all devitalised skin, fat, muscle and unattached bone is removed in a systematic sequence from superficial to deep and from the periphery of the wound to its centre. Low-pressure irrigation follows. Once debridement is complete, anything done afterwards in the same operation is treated as a clean procedure, with the limb re-prepared and fresh instruments.
Stabilisation and soft-tissue cover
Definitive soft-tissue closure or cover should be achieved within 72 hours of injury if it cannot be performed at the time of debridement.
Definitive internal stabilisation should be carried out only when it can be followed immediately by definitive soft-tissue cover — the principle often summarised as ‘fix and flap’. An implant left exposed in an open wound is the situation to avoid.
If cover is not immediate, the fracture is held with a spanning external fixator and the wound is temporarily dressed; negative pressure wound therapy may be used as a temporary dressing, but it is not a substitute for cover and does not extend the 72-hour window.
Antibiotics continue until definitive soft-tissue closure or for a maximum of 72 hours, whichever is sooner.
The Gustilo–Anderson classification
Gustilo and Anderson described three types of open fracture in 1976, and Gustilo, Mendoza and Williams subdivided type III in 1984. The classification grades the severity of the soft-tissue injury and the energy of the fracture, and the risk of infection and of non-union rises with the grade.
The Gustilo–Anderson classification of open fractures (Gustilo and Anderson 1976; Gustilo, Mendoza and Williams 1984).
Type
Definition
I
Wound less than 1 cm, clean, with minimal soft-tissue injury and a simple low-energy fracture pattern
II
Wound more than 1 cm without extensive soft-tissue damage, flaps or avulsions
IIIA
High-energy injury with extensive soft-tissue damage, but adequate soft-tissue cover of the bone after debridement; includes segmental and severely comminuted fractures whatever the size of the wound
IIIB
Extensive soft-tissue loss with periosteal stripping and exposed bone; cover of the bone is inadequate and local or free flap reconstruction is needed
IIIC
An open fracture with an arterial injury that requires repair, regardless of the size of the wound
Two points about the classification are tested more than the definitions themselves. First, the grade is assigned at surgical debridement, once the wound has been extended and the true zone of injury can be seen: the size of the skin wound in the emergency department routinely underestimates what lies beneath it. Second, the distinction between IIIA and IIIB is made by whether the bone can be covered after debridement, not by the length of the wound — and IIIC is defined by the arterial repair alone.
The classification has limits. Agreement between observers is only moderate, and it says little about function. That is one reason the UK standard does not use the grade to decide where a patient should be treated: the decision to transfer to an orthoplastic centre is based on the bone involved, not on a grade assigned in the emergency department.
Salvage or amputation
The decision between limb salvage and primary amputation in a severe injury is a multidisciplinary one, made by senior orthopaedic and plastic surgeons with the patient and family wherever possible, and with rehabilitation specialists involved early. Emergency amputation is reserved for a limb that is the source of uncontrollable life-threatening bleeding, or one that is unsalvageable. Scoring systems do not make the decision, and an insensate sole at presentation is not on its own an indication to amputate.
Test yourself
Trauma·Trauma principles, polytrauma & open fractures
easy
A 29-year-old cyclist is brought to the emergency department with an open fracture of the tibial shaft and a 6 cm wound over the anteromedial leg.
Within what time from injury should prophylactic intravenous antibiotics be administered, according to the BOAST standard?
How sure are you?
Explanation
Early antibiotic administration is the intervention most consistently shown to reduce infection after open fracture. The BOAST standard is that intravenous prophylactic antibiotics are given as soon as possible, ideally within one hour of injury, which in practice often means by the pre-hospital team; the agent follows local policy, commonly co-amoxiclav or a cephalosporin. A 3-hour threshold comes from older observational work and is no longer the standard. The 6-hour figure is the historical rule for debridement, which has not been supported by evidence, and 12 and 24 hours are the current BOAST limits for surgical debridement, not for antibiotics. Reference: BOAST, Open Fractures (2017); NICE NG37.
How quickly should antibiotics be given for an open fracture?+
As soon as possible, and ideally within one hour of injury, by the intravenous route. This is the BOAST standard and the NICE NG37 recommendation, and it often means the first dose is given by the pre-hospital team.
Is the six-hour rule for debridement still used?+
No. The BOAST standard sets three timings: immediately for highly contaminated wounds or vascular compromise, within 12 hours for solitary high-energy open fractures, and within 24 hours for other low-energy open fractures. Debridement should be done by senior orthopaedic and plastic surgeons together, in daylight hours where the timings allow.
When is the Gustilo–Anderson grade assigned?+
At surgical debridement, after the wound has been extended and the zone of injury assessed. Grading in the emergency department is unreliable because the skin wound underestimates the deeper injury.
How long are antibiotics continued?+
Until definitive soft-tissue closure, or for a maximum of 72 hours, whichever is sooner.
Which open fractures need to go to an orthoplastic centre?+
Open fractures of long bones, the hindfoot and the midfoot. Open fractures of the hand, wrist, forefoot and digits may be managed locally.
Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones. J Bone Joint Surg Am 1976;58(4):453–458.
Gustilo RB, Mendoza RM, Williams DN. Problems in the management of type III (severe) open fractures: a new classification of type III open fractures. J Trauma 1984;24(8):742–746.
Schenker ML, Yannascoli S, Baldwin KD, Ahn J, Mehta S. Does timing to operative debridement affect infectious complications in open long-bone fractures? A systematic review. J Bone Joint Surg Am 2012;94(12):1057–1064.
Brumback RJ, Jones AL. Interobserver agreement in the classification of open fractures of the tibia. J Bone Joint Surg Am 1994;76(8):1162–1166.
Eccles S, Handley B, Khan U, McFadyen I, Nanchahal J, Nayagam S (eds). Standards for the Management of Open Fractures. Oxford University Press; 2020.
Further reading
BOA Standards (BOASTs) — The open fractures standard and the related standards on compartment syndrome and arterial injury
Written for revision in the FRCS (Tr & Orth) style under our editorial standards. It is not clinical advice: always confirm against current guidance. Spotted an error? Tell us.